CCG 2979 ( CCG2979 )

产品货号. M14070 CAS No. 328070-87-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

CCG 2979
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

CCG 2979 is a small molecule inhibitor of gene expression of streptokinase (SK), a critical group A streptococcal (GAS) virulence factor.
产品描述

CCG 2979 is a small molecule inhibitor of gene expression of streptokinase (SK), a critical group A streptococcal (GAS) virulence factor; inhibits expression of SK by 60% at 50 uM based on activity assay, also inhibits the production of active SK protein; enhances granulocyte phagocytosis and killing of GAS in an in vitro assay, also protecteds mice from GAS-induced mortality in vivo.
同义词

CCG2979
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibacterial
研究领域

——
适应症

——

CAS Number

328070-87-7
分子量

394.58
分子式

C24H30N2OS
纯度

>98% (HPLC)
溶解度

——
SMILES

CCCCSC1=NC2=C(C(=O)N1CC=C)C3(CCCCC3)CC4=CC=CC=C42
化学全称

2-butylsulfanyl-3-prop-2-enylspiro[6H-benzo[h]quinazoline-5,1'-cyclohexane]-4-one

1. Sun H, et al. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3469-74.

计算器

产品手册

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